536 CHANGES IN MYOCARDIAL BIOMARKERS TO DIFFERENTIATE TYPE 2 MYOCARDIAL INFARCTION FROM TYPE 1 MYOCARDIAL INFARCTION AND ACUTE MYOCARDIAL INJURY: A PROSPECTIVE COMPARISON STUDY.

Abstract Background According to 4th Universal Definition of Myocardial Infarction (MI), it is possible differentiate clinically type 2 MI (T2MI) from 1 (T1MI) and acute myocardial injury (AMI). However, in many cases this differentiation may be difficult. To date there are poor data that allow distinguish AMI, T2MI T1MI the changes absolute or relative values biomarkers necrosis. We sought compare vs AMI terms cardiac changes. Methods we consecutively enrolled 90 patients (30 with T1MI, 30 AMI). excluding ST-segment elevation infarction. The ratio peak upper limit normal (RULN) were calculated for both CK-MB troponin T (cTnT). Moreover, cTnT was also calculated. Results peak/RULN cTnI significantly higher comparison (cTnI 100.8 67.1, p < 0.001; 2.1 0.66, 0.003) while not significant differences between (T2MI 67.1 47.3., 0.159; 0.66 0.39, 0.052). Interstingly, a rise than compared infarction, so (T1MI 196.2 20.5, 0.008). Conclusions Both peaks T2MI. Furthermore, rises out proportion These contribute better T1MI.